Rheumatoid factor (RF)
An autoantibody associated with rheumatoid arthritis and other autoimmune diseases. Presence supports diagnosis but is not specific.
Rheumatoid factor is an autoantibody—an antibody that mistakenly targets the body’s own tissues—most commonly directed against the Fc portion of immunoglobulin G (IgG). The RF test measures the level of this antibody in the blood and is primarily used to help diagnose autoimmune conditions, especially rheumatoid arthritis. However, RF may also be elevated in other inflammatory or infectious diseases, and even in some healthy individuals, particularly with aging.
Rheumatoid factor (RF)
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