Chloride (kidney)
Major extracellular anion assisting acid‑base balance. Deviations occur with metabolic disturbances and renal dysfunction.
Chloride is a negatively charged ion (anion) that works closely with other electrolytes such as sodium and potassium. It is primarily regulated by the kidneys, which adjust chloride levels through filtration and reabsorption.
Chloride plays a key role in maintaining osmotic pressure, supporting proper hydration, and helping regulate the body’s pH. It is also a component of hydrochloric acid in the stomach, aiding digestion.
Blood chloride levels are typically measured as part of a basic or comprehensive metabolic panel to assess kidney function, hydration status, and acid–base balance.

Chloride (kidney)
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