Iron binding capacity (TIBC)
A blood test that measures the body’s capacity to bind and transport iron, reflecting transferrin availability.
Total Iron-Binding Capacity (TIBC) estimates the maximum amount of iron that can be bound by proteins in the blood, primarily transferrin—the main iron transport protein. Rather than measuring iron itself, TIBC reflects how much transferrin is available to carry iron throughout the body.
It is commonly used alongside serum iron and ferritin to assess iron status and diagnose conditions such as iron deficiency or iron overload. TIBC tends to increase when the body needs more iron and decrease when iron stores are sufficient or excessive, or when certain chronic conditions affect protein production.
Iron binding capacity (TIBC)
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